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1.
BMJ Case Rep ; 14(9)2021 Sep 21.
Article in English | MEDLINE | ID: covidwho-1435024

ABSTRACT

Intraosseous schwannoma is extremely rare that it is not often considered among differential diagnosis for an osteolytic lesion, especially in long bones of the extremities. Amounting to less than 0.2% of all primary bone tumours and less than 200 cases reported so far, with only 3 cases involving the humerus, we hereby report the fourth case. In addition to its rarity, this was the only case of an intraosseous schwannoma involving the humerus bone which presented with a pathological fracture in a 45-year-old woman after sustaining a trivial trauma. Radiological examination revealed a geographic type of osteolytic lesion in distal shaft region of the left humerus. Only a histopathological examination helped in revealing and confirming the diagnosis of an intraosseous schwannoma. Treatment of the tumour with complete excision with bone graft reconstruction and osteosynthesis yields good results with very low risk of recurrence.


Subject(s)
Bone Neoplasms , Neurilemmoma , Bone Neoplasms/diagnostic imaging , Bone Neoplasms/surgery , Female , Humans , Humerus/diagnostic imaging , Humerus/surgery , Middle Aged , Neoplasm Recurrence, Local , Neurilemmoma/diagnostic imaging , Neurilemmoma/surgery , Radiography
2.
BMJ Case Rep ; 13(7)2020 Jul 08.
Article in English | MEDLINE | ID: covidwho-640059

ABSTRACT

A 17-year-old man with osteosarcoma of the proximal humerus was planned for possible limb salvage surgery after standard neoadjuvant chemotherapy. However, during the surgical phase of treatment, the COVID-19 or SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) outbreak occurred changing the healthcare landscape due to uncertainty regarding the virus, risk of COVID-19 infection and complications, and implementation of an enhanced community quarantine restricting movement of people within cities. Instead of limb salvage surgery, the patient underwent a forequarter amputation. Exposure to the virus in a high-risk hospital setting was minimised with patient discharge after a short hospital stay and home convalescence monitored by video conferencing. Multidisciplinary sarcoma team meetings with family members and a sarcoma navigator nurse were crucial in managing expectations and deciding on appropriate treatment in the setting of a novel infectious disease causing a pandemic.


Subject(s)
Amputation, Surgical/methods , Bone Neoplasms , Cisplatin/administration & dosage , Coronavirus Infections , Doxorubicin/administration & dosage , Humerus , Limb Salvage/methods , Osteosarcoma , Pandemics , Pneumonia, Viral , Adolescent , Antineoplastic Agents , Betacoronavirus , Bone Neoplasms/pathology , Bone Neoplasms/therapy , COVID-19 , Coronavirus Infections/epidemiology , Coronavirus Infections/prevention & control , Humans , Humerus/diagnostic imaging , Humerus/surgery , Magnetic Resonance Imaging/methods , Male , Neoplasm Staging , Osteosarcoma/pathology , Osteosarcoma/therapy , Pandemics/prevention & control , Patient Selection , Pneumonia, Viral/epidemiology , Pneumonia, Viral/prevention & control , SARS-CoV-2
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